Sortilin and Its Multiple Roles in Cardiovascular and Metabolic Diseases

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Sortilin and Its Multiple Roles in Cardiovascular and Metabolic Diseases.

Cardiovascular disease is a leading cause of morbidity and mortality in the Western world. Studies of sortilin's influence on cardiovascular and metabolic diseases goes far beyond the genome-wide association studies that have revealed an association between cardiovascular diseases and the 1p13 locus that encodes sortilin. Emerging evidence suggests a significant role of sortilin in the pathogen...

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ژورنال

عنوان ژورنال: Arteriosclerosis, Thrombosis, and Vascular Biology

سال: 2018

ISSN: 1079-5642,1524-4636

DOI: 10.1161/atvbaha.117.310292